SOC status:Duty analyst on shift

UK Cyber Defence
VulnerabilityAnalyzed

CVE-2026-100845

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files.

HIGH 8.5EPSS 0.20%

Does this matter?

High impact if exploited, but EPSS currently rates exploitation as unlikely (0.20%). Schedule it in the normal patch cycle and watch for a rise in EPSS or a public exploit.

Description

MONAI before 1.6.0 contains an unsafe deserialization vulnerability in the NumpyReader class that unconditionally uses numpy.load with allow_pickle=True when loading .npy and .npz files. Attackers can craft malicious .npy files with pickle payloads that execute arbitrary code when loaded through MONAI's standard data pipeline.

CVSS 4.0
8.5 HIGHCVSS:4.0/AV:L/AC:L/AT:N/PR:N/UI:P/VC:H/VI:H/VA:H/SC:N/SI:N/SA:N/E:X/CR:X/IR:X/AR:X/MAV:X/MAC:X/MAT:X/MPR:X/MUI:X/MVC:X/M
EPSS
0.20% probability · 10th percentile
Public exploits
None in Exploit-DB
CISA KEV
Not listed
Weakness
CWE-502
Affected
project-monai/monai
Source
disclosure@vulncheck.com
EPSS trend
0%3%5%27 September 2026: 0.14%27 October 2026: 0.20%27 September 202627 October 2026

EPSS moved from 0.1% on 27 September 2026 to 0.2% on 27 October 2026.

Source: NVD record, EPSS from FIRST.org, KEV from CISA, exploits from Exploit-DB. Refreshed daily. Download this record as JSON.