CVE-2025-50675
GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory.
Does this matter?
High impact if exploited, but EPSS currently rates exploitation as unlikely (0.23%). Schedule it in the normal patch cycle and watch for a rise in EPSS or a public exploit.
Description
GPMAW 14, a bioinformatics software, has a critical vulnerability related to insecure file permissions in its installation directory. The directory is accessible with full read, write, and execute permissions for all users, allowing unprivileged users to manipulate files within the directory, including executable files like GPMAW3.exe, Fragment.exe, and the uninstaller GPsetup64_17028.exe. An attacker with user-level access can exploit this misconfiguration by replacing or modifying the uninstaller (GPsetup64_17028.exe) with a malicious version. While the application itself runs in the user's context, the uninstaller is typically executed with administrative privileges when an administrator attempts to uninstall the software. By exploiting this flaw, an attacker could gain administrative privileges and execute arbitrary code in the context of the admin, resulting in privilege escalation.
- CVSS 3.1
- 7.8 HIGHCVSS:3.1/AV:L/AC:L/PR:L/UI:N/S:U/C:H/I:H/A:H
- EPSS
- 0.23% probability · 14th percentile
- CISA KEV
- Not listed
- Weakness
- CWE-732
- Source
- cve@mitre.org
References
Source: NVD record, EPSS from FIRST.org, KEV from CISA. Refreshed daily.